Destructive Eyelid Lesions in Sarcoidosis

Ophthalmic Plastic and Reconstructive Surgery
Vol. 17, No. 2, pp 123–125 ©2001 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.

Muhammad Moin, F.R.C.Ophth.,* Robert C. Kersten, M.D.,* Francesco Bernardini, M.D.,* and Dwight R. Kulwin, M.D.*

*Department of Ophthalmology, University of Cincinnati, Ohio; †Department of Ophthalmology, Mayo Hospital, Lahore, Pakistan; Cincinnati Eye Institute, Cincinnati, Ohio; and Department of Ophthalmology, University of Genoa, Italy

Purpose:
To report the clinical and histopathologic findings of a patient with sarcoidosis causing bilateral destruction of the lower eyelids.

Methods:
Case report.

Results:
Bilateral destructive lower eyelid lesions and cicatricial entropion developed in a 43-year-old man with systemic sarcoidosis. Histopathology was consistent with sarcoid granulomas.

Disease progression was arrested with systemic prednisone and methotrexate before eyelid reconstruction was performed.

Conclusions:
Sarcoidosis very rarely can cause destruction of full-thickness eyelid architecture. Active inflammation should be controlled before reconstruction.

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About the author

Specialista in Oftalmologia e chirurgo plastico oculofacciale. Si è formato negli Stati Uniti con una fellowship chirurgica di due anni all'Università di Cincinnati (Ohio). È membro della American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS), dell'AICPE e della Orbital Society, professore a contratto alla Scuola di specializzazione in Oftalmologia dell'IRCCS Ospedale San Raffaele di Milano e membro dell'Editorial Board della rivista Ophthalmic Plastic and Reconstructive Surgery (OPRS). Opera a Genova e Milano.